產(chǎn)品資料

首頁(yè) >>> 產(chǎn)品目錄 >>> 試劑 >>> abm

NANOG Lysate

點(diǎn)擊看大圖

如果您對(duì)該產(chǎn)品感興趣的話,可以

產(chǎn)品名稱: NANOG Lysate

產(chǎn)品型號(hào):

產(chǎn)品展商: 其他品牌

產(chǎn)品文檔: 無相關(guān)文檔

簡(jiǎn)單介紹

NANOG Lysate

NANOG Lysate 的詳細(xì)介紹

	Print Version
Organism	Human
Accession #	Q9H9S0
Alias	Homeobox protein NANOG
Protein Type	Wild Type
Protein Sequence	HHHHHHSVDPACPQSLPCFEASDCKESSPMPVICGPEENYPSLQMSSAEMPHTETVSPLPSSMDLLIQDSPDSSTSPKGKQPTSAEKSVAKKEDKVPVKKQKTRTVFSSTQLCVLNDRFQRQKYLSLQQMQELSNILNLSYKQVKTWFQNQRMKSKRWQKNNWPKNSNGVTQKASAPTYPSLYSSYHQGCLVNPTGNLPMWSNQTWNNSTWSNQTQNIQSWSNHSWNTQTWCTQSWNNQAWNSPFYNCGEESLQSCMQFQPNSPASDLEAALEAAGEGLNVIQQTTRYFSTPQTMDLFLNYSMNMQPEDVESGGGGSPGRRRRRRRRR
Protein Family	Belongs to the Nanog homeobox family.
Functions	? Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Nanog imposes pluripotency on ES cells and prevents their differentiation towards extra-embryonic endoderm and trophectoderm lineages. It also blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. When NANOG is overexpressed, it promotes cells to enter into S phase and proliferation. ? NANOG is one of the four factors in the Thomson protocol for iPSC reprogramming. The recombinant protein within the lysate has a 6X His tag at N-terminus for purification and 9X Arginine at C-terminus for cell membrane penetration.
Cell Types	Expressed in testicular carcinoma and derived germ cell tumors (at protein level). Expressed in fetal gonads, ovary and testis. Also expressed in ovary teratocarcinoma cell line and testicular embryonic carcinoma. Not expressed in many somatic organs and oocytes.
Protein Location	Nucleus.
Tag	6X His tag at N-terminus and 9X Poly-Arginine at C-terminus
Form	Liquid
Expression System	E.coli
Type	Lysate
Purification	None
Quality Control	By Western Blot Analysis
Concentration	1mg/ml
Storage	DMEM with 2.5% glycerol
Shipping	On dry ice.
Notes	For Research Use Only, not for therapeutic or diagnostic purposes.
References	Induced pluripotent stem cell lines derived from human somatic cells. Yu et al. Science. 2007 Dec 21;318(5858):1917-20. Epub 2007 Nov 20. Human induced pluripotent stem cells free of vector and transgene sequences. Yu et al. Science. 2009 May 8;324(5928):797-801. Epub 2009 Mar 26.

產(chǎn)品留言

標(biāo)題

聯(lián)系人

聯(lián)系電話

內(nèi)容

驗(yàn)證碼

點(diǎn)擊換一張

注：1.可以使用快捷鍵Alt+S或Ctrl+Enter發(fā)送信息!
2.如有必要,請(qǐng)您留下您的詳細(xì)聯(lián)系方式!

相關(guān)產(chǎn)品

abmgood|G499

abmgood|G463

abmgood|G232

abmgood|G237

abmgood| G902

abmgood|G905

abmgood|E002

abmgood|2X PCR Taq Plus MasterMix

abmgood|TaqFast DNA Polymerase

abmgood|2X PCR Taq Plus MasterMix with dye

abmgood|2X PCR TaqFast MasterMix

abmgood|2X PCR TaqFast MasterMix with dye

abmgood|Bestaq ; DNA Polymerase

abmgood|2X PCR Bestaq ; MasterMix

abmgood|2X PCR Bestaq ; MasterMix with dye

abmgood|Kodaq DNA Polymerase

abmgood|Kodaq 2X PCR MasterMix

abmgood|Kodaq 2X PCR MasterMix with Dye

abmgood|Bloodirect DNA Polymerase

abmgood|Bloodirect 2X PCR MasterMix

abmgood|Tissue Ex-Amp PCR Kit

abmgood|Plant Ex-Amp PCR Kit

abmgood|PCR-Sure ; Kit

abmgood|SafeView Plus?

abmgood|Safeview FireRed

abmgood|SafeView?

abmgood|OneScript ; Reverse Transcriptase

abmgood|OneScript Plus ; Reverse Transcriptase

abmgood|5X All-In-One RT MasterMix

abmgood|5X All-In-One MasterMix (with AccuRT Genomic DNA Removal Kit)

abmgood|miRNA cDNA Synthesis Kit, with Poly(A) Polymerase Tailing

abmgood|Total-Transcriptome cDNA Synthesis Kit

abmgood|EvaGreen 2X qPCR MasterMix-iCycler

abmgood|EvaGreen 2X qPCR MasterMix-Low ROX

abmgood|EvaGreen 2X qPCR MasterMix-no DYE

abmgood|EvaGreen Express 2X qPCR MasterMix-ROX

abmgood|EvaGreen 2X qPCR MasterMix-ROX

abmgood|EvaGreen Express 2X qPCR MasterMix-Low ROX

abmgood|EvaGreen Express 2X qPCR MasterMix-iCycler

abmgood|EvaGreen Express 2X qPCR MasterMix-No Dye

abmgood|EvaGreen miRNA qPCR Mastermix-iCycler

abmgood|EvaGreen miRNA qPCR Mastermix-low ROX

abmgood|EvaGreen miRNA qPCR Mastermix-ROX

abmgood|EvaGreen miRNA qPCR Mastermix-no dye

abmgood|TaqProbe 2X qPCR MasterMix-ROX

abmgood|TaqProbe 2X qPCR MasterMix-iCycler

abmgood|TaqProbe 2X qPCR MasterMix-Low ROX

abmgood|TaqProbe 2X qPCR MasterMix-Multiplex

abmgood|TaqProbe 2X qPCR MasterMix-No Dye

ABMgood 授權(quán)簽約代理