Iberiotoxin
Blocker of high conductance Ca2+-activated K+ channel
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產(chǎn)品名稱: Iberiotoxin
Blocker of high conductance Ca2+-activated K+ channel
產(chǎn)品型號(hào): 12IBX001-50010
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Iberiotoxin
Blocker of high conductance Ca2+-activated K+ channel
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Iberiotoxin
Blocker of high conductance Ca2+-activated K+ channel
Iberiotoxin (IbTx) is a toxin that was originally isolated from Buthus tamulus scorpion venom. Iberiotoxin inhibits selectively the high conductance Ca2+-activated K+ channel (KCa1.1) at nanomolar concentrations (IC50 ~2 nM). This toxin does not affect other types of calcium-dependent or voltage-dependent K+ channels. Iberiotoxin is a valuable tool to study specifically Maxi-K channels.