Product Name
SLC37A4, Polyclonal Antibody
Full Product Name
SLC37A4 Antibody
Product Synonym Names
G6PT1; G6PT2; G6PT3; GSD1b; GSD1c; GSD1d; TRG19; TRG-19; PRO0685
Product Gene Name
anti-SLC37A4 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O43826
Specificity
The antibody detects endogenous levels of total SLC37A4 protein.
Purity/Purification
Antigen affinity purification
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.4mg/ml (lot specific)
Immunogen
Synthetic peptide of human SLC37A4
Preparation and Storage
Store at -20 degree C.
Other Notes
Small volumes of anti-SLC37A4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SLC37A4 antibody
This gene regulates glucose-6-phosphate transport from the cytoplasm to the lumen of the endoplasmic reticulum, in order to maintain glucose homeostasis. It also plays a role in ATP-mediated calcium sequestration in the lumen of the endoplasmic reticulum. Mutations in this gene have been associated with various forms of glycogen storage disease. Alternative splicing in this gene results in multiple transcript variants.
Product Categories/Family for anti-SLC37A4 antibody
Total protein Ab
Applications Tested/Suitable for anti-SLC37A4 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SLC37A4 antibody
WB:1:200-1000
IF: 1: 20-100
SDS-Page of anti-SLC37A4 antibody
Gel: 8%SDS-PAGE Lysate: 40 μg, Lane: Mouse brain tissue lysate Primary antibody:EHD3 Antibody at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 minutes
NCBI/Uniprot data below describe general gene information for SLC37A4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001157749
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NCBI GenBank Nucleotide #
NM_001164277.1
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UniProt Primary Accession #
O43826
[Other Products]
UniProt Secondary Accession #
O96016; Q5J7V4; Q9UI19; Q9UNS4[Other Products]
UniProt Related Accession #
O43826[Other Products]
NCBI Official Full Name
glucose-6-phosphate exchanger SLC37A4 isoform 1
NCBI Official Synonym Full Names
solute carrier family 37 member 4
NCBI Official Symbol
SLC37A4??[Similar Products]
NCBI Official Synonym Symbols
G6PT1; G6PT2; G6PT3; GSD1b; GSD1c; GSD1d; TRG19; TRG-19; PRO0685
??[Similar Products]
NCBI Protein Information
glucose-6-phosphate exchanger SLC37A4
UniProt Protein Name
Glucose-6-phosphate exchanger SLC37A4
UniProt Synonym Protein Names
Glucose-5-phosphate transporter; Glucose-6-phosphate translocase
Protein Family
Glucose-6-phosphate exchanger
UniProt Gene Name
SLC37A4??[Similar Products]
UniProt Synonym Gene Names
TRG-19??[Similar Products]
NCBI Summary for SLC37A4
This gene regulates glucose-6-phosphate transport from the cytoplasm to the lumen of the endoplasmic reticulum, in order to maintain glucose homeostasis. It also plays a role in ATP-mediated calcium sequestration in the lumen of the endoplasmic reticulum. Mutations in this gene have been associated with various forms of glycogen storage disease. Alternative splicing in this gene results in multiple transcript variants.[provided by RefSeq, Aug 2009]
UniProt Comments for SLC37A4
Inorganic phosphate and glucose-6-phosphate antiporter of the endoplasmic reticulum. Transports cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocates inorganic phosphate into the opposite direction. Forms with glucose-6-phosphatase the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels.
Research Articles on SLC37A4
1. We report the MFRP-related ocular phenotype in three siblings with glycogen storage disease type 1b. Molecular genetic studies identified novel mutations in the MFRP and SLC37A4 genes.
Precautions
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Disclaimer
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