Product Name
Ferritin Heavy Chain (FTH1), Polyclonal Antibody
Full Product Name
Ferritin Heavy Chain Antibody
Product Synonym Names
FTH1; Apoferritin; Ferritin H subunit; Ferritin heavy chain; Ferritin; heavy polypeptide 1; FHC; FTHL6; PIG15; PLIF; FTH
Product Gene Name
anti-FTH1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P02794
Specificity
Ferritin Heavy Chain Antibody detects endogenous levels of total Ferritin Heavy Chain
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (lot specific)
Immunogen
A synthesized peptide derived from human Ferritin Heavy Chain
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-FTH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-FTH1 antibody
Total protein Ab
Applications Tested/Suitable for anti-FTH1 antibody
Western Blot (WB)
Application Notes for anti-FTH1 antibody
Western Blot: 1:1000-3000
Western Blot (WB) of anti-FTH1 antibody
Western blot analysis Ferritin Heavy Chain using K562 whole cell lysates
NCBI/Uniprot data below describe general gene information for FTH1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002023.2
[Other Products]
NCBI GenBank Nucleotide #
NM_002032.2
[Other Products]
UniProt Primary Accession #
P02794
[Other Products]
UniProt Secondary Accession #
Q3KRA8; Q3SWW1; B3KNR5[Other Products]
UniProt Related Accession #
P02794[Other Products]
Molecular Weight
21,226 Da[Similar Products]
NCBI Official Full Name
ferritin heavy chain
NCBI Official Synonym Full Names
ferritin heavy chain 1
NCBI Official Symbol
FTH1??[Similar Products]
NCBI Official Synonym Symbols
FHC; FTH; HFE5; PLIF; FTHL6; PIG15
??[Similar Products]
NCBI Protein Information
ferritin heavy chain
UniProt Protein Name
Ferritin heavy chain
UniProt Synonym Protein Names
Cell proliferation-inducing gene 15 protein
UniProt Gene Name
FTH1??[Similar Products]
UniProt Synonym Gene Names
FTH; FTHL6; Ferritin H subunit??[Similar Products]
UniProt Entry Name
FRIH_HUMAN
NCBI Summary for FTH1
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their
biological validity has not been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for FTH1
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney ().
Research Articles on FTH1
1. Ferritin light chain and ferritin heavy chain are required for the neural differentiation of bone marrow-derived mesenchymal stem cells under extremely low-frequency electromagnetic field.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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