Product Name
Ferritin heavy chain (Fth1), ELISA Kit
Full Product Name
Rat Ferritin heavy chain ELISA Kit
Product Synonym Names
Ferritin heavy chain; Ferritin H subunit; Fth1; Fth; 1.16.3.1
Product Gene Name
Fth1 elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for P19132
Detection Range
6.25-400 ng/mL
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of Fth1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for Fth1 purchase
MBS2886777 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ferritin heavy chain (Fth1) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Fth1. The ELISA analytical biochemical technique of the MBS2886777 kit is based on Fth1 antibody-Fth1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Fth1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Fth1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Typical Testing Data/Standard Curve (for reference only) of Fth1 elisa kit
NCBI/Uniprot data below describe general gene information for Fth1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_036980.1
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NCBI GenBank Nucleotide #
NM_012848.2
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UniProt Primary Accession #
P19132
[Other Products]
UniProt Related Accession #
P19132[Other Products]
Molecular Weight
21,127 Da
NCBI Official Full Name
ferritin heavy chain
NCBI Official Synonym Full Names
ferritin, heavy polypeptide 1
NCBI Official Symbol
Fth1??[Similar Products]
NCBI Official Synonym Symbols
Fth
??[Similar Products]
NCBI Protein Information
ferritin heavy chain
UniProt Protein Name
Ferritin heavy chain
UniProt Gene Name
Fth1??[Similar Products]
UniProt Synonym Gene Names
Fth; Ferritin H subunit??[Similar Products]
UniProt Entry Name
FRIH_RAT
NCBI Summary for Fth1
overexpressed during hepatic tumor development; used as an early marker for hepatocellular carcinoma [RGD, Feb 2006]
UniProt Comments for Fth1
Ferritin-H: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited. Belongs to the ferritin family.
Protein type: EC 1.16.3.1; Oxidoreductase; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll
Cellular Component: cell; mitochondrion; nucleus
Molecular Function: ferric iron binding; ferroxidase activity; protein binding
Biological Process: cellular iron ion homeostasis; immune response; intracellular sequestering of iron ion; iron ion transport; negative regulation of cell proliferation; negative regulation of fibroblast proliferation
Research Articles on Fth1
1. This work demonstrates the key role of the cytokine IL-1beta in the regulation of a novel intracellular mediator [i.e., the protein ferritin heavy chain (FHC)] of HIV-induced dendritic damage and the resulting neurocognitive impairment.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
