Product Name
EIF1AX, Polyclonal Antibody
Full Product Name
EIF1AX antibody - middle region
Product Gene Name
anti-EIF1AX antibody
[Similar Products]
Product Synonym Gene Name
EIF1A; EIF4C; eIF-1A; eIF-4C; EIF1AP1[Similar Products]
Antibody/Peptide Pairs
EIF1AX peptide (MBS3232986) is used for blocking the activity of EIF1AX antibody (MBS3208023)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: KYNADEARSL KAYGELPEHA KINETDTFGP GDDDEIQFDD IGDDDEDIDD
3D Structure
ModBase 3D Structure for P47813
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Yeast, Zebrafish
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 92%; Zebrafish: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human EIF1AX
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-EIF1AX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-EIF1AX antibody
This is a rabbit polyclonal antibody against EIF1AX. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA.
Product Categories/Family for anti-EIF1AX antibody
Polyclonal; RNA Binding Proteins; Drugs and Drug Metabolism; DNA/RNA/Protein Interactions;
Applications Tested/Suitable for anti-EIF1AX antibody
Western Blot (WB)
Western Blot (WB) of anti-EIF1AX antibody
WB Suggested Anti-EIF1AX Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:2500
Positive Control: Human brain
NCBI/Uniprot data below describe general gene information for EIF1AX. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001403
[Other Products]
NCBI GenBank Nucleotide #
NM_001412
[Other Products]
UniProt Primary Accession #
P47813
[Other Products]
UniProt Related Accession #
P47813[Other Products]
NCBI Official Full Name
eukaryotic translation initiation factor 1A, X-chromosomal
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 1A X-linked
NCBI Official Symbol
EIF1AX??[Similar Products]
NCBI Official Synonym Symbols
EIF1A; EIF4C; eIF-1A; eIF-4C; EIF1AP1
??[Similar Products]
NCBI Protein Information
eukaryotic translation initiation factor 1A, X-chromosomal
UniProt Protein Name
Eukaryotic translation initiation factor 1A, X-chromosomal
UniProt Synonym Protein Names
Eukaryotic translation initiation factor 4C; eIF-4C
Protein Family
Eukaryotic translation initiation factor
UniProt Gene Name
EIF1AX??[Similar Products]
UniProt Synonym Gene Names
EIF1A; EIF4C; eIF-1A X isoform; eIF-4C??[Similar Products]
UniProt Entry Name
IF1AX_HUMAN
NCBI Summary for EIF1AX
This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA. [provided by RefSeq, Jul 2008]
UniProt Comments for EIF1AX
EIF1AX: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. Belongs to the eIF-1A family
Protein type: Translation initiation; Translation; RNA-binding
Chromosomal Location of Human Ortholog: Xp22.12
Cellular Component: cytosol
Molecular Function: protein binding; translation factor activity, nucleic acid binding; translation initiation factor activity
Biological Process: cellular protein metabolic process; translation; translational initiation; gene expression
Research Articles on EIF1AX
1. Its mutation is found in patients with meningeal melanocytic tumor.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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