Product Name
EIF1AX, Polyclonal Antibody
Full Product Name
Anti-EIF1AX Antibody
Product Synonym Names
EIF1A; EIF4C; Eukaryotic translation initiation factor 1A, X-chromosomal; eIF-1A X isoform; Eukaryotic translation initiation factor 4C; eIF-4C
Product Gene Name
anti-EIF1AX antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P47813
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of EIF1AX protein.
Purity/Purification
Purified by immunogen affinity chromatography
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
Recombinant full length protein of human EIF1AX
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-EIF1AX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-EIF1AX antibody
Rabbit polyclonal antibody to EIF1AX
Applications Tested/Suitable for anti-EIF1AX antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-EIF1AX antibody
WB: 1/500 - 1/2000
IHC: 1/50 - 1/200
Western Blot (WB) of anti-EIF1AX antibody
Western blot analysis of EIF1AX expression in HT29 (A), MCF7 (B), mouse brain (C) whole cell lysates.
NCBI/Uniprot data below describe general gene information for EIF1AX. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001403.1
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NCBI GenBank Nucleotide #
NM_001412.3
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UniProt Primary Accession #
P47813
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UniProt Secondary Accession #
Q0VGC2; Q5JPS5; Q5JPS6; B2R5U5[Other Products]
UniProt Related Accession #
P47813[Other Products]
Molecular Weight
16,460 Da
NCBI Official Full Name
eukaryotic translation initiation factor 1A, X-chromosomal
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 1A, X-linked
NCBI Official Symbol
EIF1AX??[Similar Products]
NCBI Official Synonym Symbols
EIF1A; EIF4C; eIF-1A; eIF-4C; EIF1AP1
??[Similar Products]
NCBI Protein Information
eukaryotic translation initiation factor 1A, X-chromosomal
UniProt Protein Name
Eukaryotic translation initiation factor 1A, X-chromosomal
UniProt Synonym Protein Names
Eukaryotic translation initiation factor 4C; eIF-4C
Protein Family
Eukaryotic translation initiation factor
UniProt Gene Name
EIF1AX??[Similar Products]
UniProt Synonym Gene Names
EIF1A; EIF4C; eIF-1A X isoform; eIF-4C??[Similar Products]
NCBI Summary for EIF1AX
This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA. [provided by RefSeq, Jul 2008]
UniProt Comments for EIF1AX
Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
Research Articles on EIF1AX
1. Coexpression of mutant NRAS and EIF1AX proteins promoted proliferation and clonogenic survival in LGSC cells, providing the first example of co-occurring, growth-promoting mutational events in ovarian cancer.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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