Product Name
TUBB2B, Polyclonal Antibody
Full Product Name
TUBB2B Antibody - N-terminal region
Product Gene Name
anti-TUBB2B antibody
[Similar Products]
Product Synonym Gene Name
DKFZp566F223; FLJ98847; MGC8685; TUBB-PARALOG; bA506K6.1[Similar Products]
Antibody/Peptide Pairs
TUBB2B peptide (MBS3241872) is used for blocking the activity of TUBB2B antibody (MBS3216973)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: GGGTGSGMGT LLISKIREEY PDRIMNTFSV MPSPKVSDTV VEPYNATLSV
3D Structure
ModBase 3D Structure for Q9BVA1
Species Reactivity
Cow, Human, Mouse, Rat, Sheep
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Sheep: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human TUBB2B
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-TUBB2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TUBB2B antibody
This is a rabbit polyclonal antibody against TUBB2B. It was validated on Western Blot
Target Description: The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria.
Product Categories/Family for anti-TUBB2B antibody
Polyclonal; Disease Related;
Applications Tested/Suitable for anti-TUBB2B antibody
Western Blot (WB)
Western Blot (WB) of anti-TUBB2B antibody
Host: Rabbit
Target Name: TUBB2B
Sample Tissue: Human MCF7 Whole Cell
Antibody Dilution: 1ug/ml
Western Blot (WB) of anti-TUBB2B antibody
WB Suggested Anti-TUBB2B Antibody
Titration: 1.0 ug/ml
Positive Control: MCF7 Whole Cell
NCBI/Uniprot data below describe general gene information for TUBB2B. It may not necessarily be applicable to this product.
NCBI Accession #
NP_821080
[Other Products]
NCBI GenBank Nucleotide #
NM_178012
[Other Products]
UniProt Primary Accession #
Q9BVA1
[Other Products]
UniProt Related Accession #
Q9BVA1[Other Products]
NCBI Official Full Name
tubulin beta-2B chain
NCBI Official Synonym Full Names
tubulin beta 2B class IIb
NCBI Official Symbol
TUBB2B??[Similar Products]
NCBI Official Synonym Symbols
CDCBM7; PMGYSA; bA506K6.1
??[Similar Products]
NCBI Protein Information
tubulin beta-2B chain
UniProt Protein Name
Tubulin beta-2B chain
UniProt Gene Name
TUBB2B??[Similar Products]
NCBI Summary for TUBB2B
The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria. [provided by RefSeq, Mar 2010]
UniProt Comments for TUBB2B
Tubulin is the major constituent of microtubules (PubMed:23001566, PubMed:28013290, PubMed:26732629). It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (). Plays a critical role in proper axon guidance in both central and peripheral axon tracts (PubMed:23001566). Implicated in neuronal migration (PubMed:19465910).
Research Articles on TUBB2B
1. CPAP regulates delivery of its bound beta-tubulin to define the size of microtubule-based cellular structures using a "clutch-like" mechanism.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
