Product Name
TUBB2B, cDNA Clone
Full Product Name
TUBB2B cDNA Clone
Product Gene Name
TUBB2B cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgcgtgaga tcgtgcacat ccaggcgggc cagtgcggca accagatcgg cgccaagttt tgggaggtca tcagtgatga gcatgggatt gaccccactg gcagttacca tggagacagt gatttgcagc tggagagaat caatgtttac tacaatgaag ccactggtaa caaatatgtt cctcgggcca tcctcgtgga tctggagcca ggcacgatgg attcggttag gtctggacca ttcggccaga tcttcagacc agacaatttc gtgtttggcc agagtggagc cgggaataac tgggccaagg gccactacac agagggagcc gagctggtcg actcggtcct ggatgtggtg aggaaggagt cagagagctg tgactgtctc cagggcttcc agctgaccca ctctctgggg ggcggcacgg ggtccgggat gggcaccctg ctcatcagca agatccggga agagtaccca gaccgcatca tgaacacctt cagcgtcatg ccctcaccca aggtgtcaga cacggtggtg gagccctaca acgccaccct ctcggtccac cagctggtgg aaaacacaga tgaaacctac tgcattgaca acgaggccct gtatgacatc tgcttccgca ccctgaagct gaccaccccc acctacgggg acctcaacca cctggtgtcg gccaccatga gcggggtcac cacctgcctg cgcttcccgg gccagctgaa cgcagacctg cgcaagctgg cggtgaacat ggtgcccttc cctcgcctgc acttcttcat gcccggcttc gcgcccctga ccagccgggg cagccagcag taccgggcgc tcacggtgcc cgagctcacc cagcagatgt tcgactccaa gaacatgatg gccgcctgcg acccgcgcca cggccgctac ctgacggtgg ctgccatctt ccggggccgc atgtccatga aggaggtgga cgagcagatg ctcaacgtgc agaacaagaa cagcagctac ttcgtggagt ggatccccaa caacgtgaag acggccgtgt gcgacatccc gccccgcggc ctgaagatgt cggccacctt catcggcaac agcacggcca tccaggagct gttcaagcgc atctccgagc agttcacggc catgttccgg cgcaaggcct tcctgcactg gtacacgggc gagggcatgg acgagatgga gttcaccgag gccgagagca acatgaacga cctggtgtcc gagtaccagc agtaccagga cgccacggcc gacgaacaag gggagttcga ggaggaggag ggcgaggacg aggcgtag
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of TUBB2B cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for TUBB2B. It may not necessarily be applicable to this product.
NCBI Accession #
BC001352
[Other Products]
UniProt Secondary Accession #
A8K068[Other Products]
UniProt Related Accession #
Q9BVA1[Other Products]
Molecular Weight
49,953 Da
NCBI Official Full Name
Homo sapiens tubulin, beta 2B, mRNA
NCBI Official Synonym Full Names
tubulin beta 2B class IIb
NCBI Official Symbol
TUBB2B??[Similar Products]
NCBI Official Synonym Symbols
PMGYSA; bA506K6.1
??[Similar Products]
NCBI Protein Information
tubulin beta-2B chain
UniProt Protein Name
Tubulin beta-2B chain
UniProt Gene Name
TUBB2B??[Similar Products]
UniProt Entry Name
TBB2B_HUMAN
NCBI Summary for TUBB2B
The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria. [provided by RefSeq, Mar 2010]
UniProt Comments for TUBB2B
TUBB2B: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB2B is implicated in neuronal migration. Defects in TUBB2B are a cause of polymicrogyria asymmetric (PMGA). PMGA is a malformation of the cortex in which the brain surface is irregular and characterized by an excessive number of small gyri with abnormal lamination. Belongs to the tubulin family.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 6p25
Cellular Component: microtubule; nucleus
Molecular Function: protein binding
Biological Process: neuron migration
Disease: Polymicrogyria, Symmetric Or Asymmetric
Research Articles on TUBB2B
1. off-target, non-immune mediated effects of the mTOR-inhibitor everolimus on the podocyte cytoskeleton might involve regulation of microtubules, revealing a potential novel role of TUBB2B and DCDC2 in glomerular podocyte development
Precautions
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Disclaimer
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